Refine your search
Collections
Co-Authors
Journals
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Denkova, Zapriana
- Antimicrobial Testings and Gas Chromatoaraphic Analysis of Pure Oxygenated Monoterpenes 1.8-Cineole, α-Terpineol, Terpinen-4-ol and Camphor as Well as Target Compounds in Essential Oils of Pine (Pinus pinaster), Rosemary (Rosmarinus officinalis), Tea
Abstract Views :180 |
PDF Views:0
Authors
Leopold Jirovetz
1,
Gerhard Buchbauer
1,
Zapriana Denkova
2,
Albena Stoyanova
2,
Ivan Murgov
2,
Erich Schmidt
3,
Margit Geissler
4
Affiliations
1 Department of Pharmaceutical Chemistry, University of Vienna, Althanstrasse 14, A-1090 Vienna, AT
2 University of Food Technology, Department of Essential Oils, 26 Maritza Boulevard, 4002 Plovdiv, BG
3 Kur Ktitzing GmbH, Hinterm Alten Schloss 21, D-86757 Wallerstein, DE
4 SHIMADZU Germany, Department of GC and GC/MS, Albert-Hahn-Strasse 6-10, D-47269 Duisburg, DE
1 Department of Pharmaceutical Chemistry, University of Vienna, Althanstrasse 14, A-1090 Vienna, AT
2 University of Food Technology, Department of Essential Oils, 26 Maritza Boulevard, 4002 Plovdiv, BG
3 Kur Ktitzing GmbH, Hinterm Alten Schloss 21, D-86757 Wallerstein, DE
4 SHIMADZU Germany, Department of GC and GC/MS, Albert-Hahn-Strasse 6-10, D-47269 Duisburg, DE
Source
Scientia Pharmaceutica, Vol 73, No 1 (2005), Pagination: 27-38Abstract
The oxygenated monoterpenes 1,8-cineole, α-terpineol, terpinen-4-ol and camphor as well as essential oils of pine, rosemary and tea tree, rich in these volatiles, were tested for their antimicrobial activities against some different strains of yeast, Gram-(-)- and Gram-(+)-bacteria by agar diffusion and agar dilution method, respectively. The same was done using the phenolic aroma compound eugenol as a reference-substance. The monoterpene alcohols α-terpineol and terpinen-4-ol were found to be active against all strains used in a wide range. The same result was obtained for the testings of essential oils of pine, rosemary (2 samples) and tea tree. Nearly all aroma chemicals and essential oils did show a significant high antimicrobial activity against Staphylococcus aureus and Pseudomonas aeruginosa. For qualitative and quantitaive investigations of the key aroma compounds and the compositions of the essential oils, gas chromatographic methods (GC-FID and GCMS with columns of different polarities) were used and the results correlated with that of the antimicrobial testings. The obtained data are discussed to get more insight into the influence of pure aroma compounds on antimicrobial activities of essential oils.Keywords
Essential Pine Oil, Essential Rosemary Oils, Essential Tea Tree Oil, Oxygenated Monoterpenes, Antimicrobial Testing, GC
References
- Jirovetz, L., 34th International Symposium on Essential Oils, September 10th, 2003, Lecture 18, Wuerzburg, Germany.
- Jirovetz, L., Buchbauer, G., Stoyanova, A., Denkova, Z., Murgov, I., EURO COSMETICS 12 (1), 30-33 (2004).
- Jirovetz, L., Buchbauer, G., Stoyanova, A., Denkova, Z., Murgov, I., Ernaehrung/Nutrition 28 (6), 257-260 (2004).
- Jirovetz, L., Buchbauer, G., Stoyanova, A., Denkova, Z., Murgov, I., Schmidt, E., Geissler, M., J. Essent. Oil-Bearing Plants, in press (2004).
- Jirovetz, L., Buchbauer, G., Stoyanova, A., Denkova, Z., Murgov, I., Schmidt, E., Geissler, M., III International Symposium Breeding Research on Medicinal and Aromatic Plants (ISMAP), July 5-8, 2004, Poster 136, Campinas, Brasil.
- Schmidt, E., Jirovetz, L., Buchbauer, G., Stoyanova, A., Denkova, Z., Murgov, I., Geissler, M., 35th International Symposium on Essential Oils, September 8-10, 2004, Poster 76, Messina, Italy.
- Bauer, K., Garbe, D., Surburg, H. Common Fragrance and Flavor Materials, 3rd Ed., VCH, Weinheim (1997).
- Connolly, J.D., Hill, R.A., Dictionary of Terpenoids, Vol. 1: Mono- and Sesquiterpenoids, Chapman & Hall, London (1991).
- Finnemore, H., The Essential Oils, Ernest Benn Ltd., London (1927).
- Furia, T.E., Bellanca, N. (Eds.), Fenaroli's Handbook of Flavour Ingredients, 2nd Edition, Vol. I, CRC Press, Cleveland (1975).
- Gildemeister, E., Hoffmann, Fr., Die Aetherischen Oele, Vol. IV, Akademie-Verlag, Berlin (1956).
- Osterreichisches Arzneibuch (Pharmacopoae Austriaca) 1981, 1. Nachtrag, 213-215, Aetheroleum Rosmarini, Staatsdruckerei, Wien (1981).
- Osterreichisches Anneibuch (Pharmacopoae Austriaca) 1990, 12. Nachtrag, Aetheroleum Terebinthinae rectificatum, Verlag Oesterreich, Wien (2004).
- Macchioni, F., Cioni, P.L., Flamini, G., Morelli, I., Maccioni, S., Ansaldi, M., Flavour Fragr. J. 18, 139-143 (2003).
- Reichling, J., Harkenthal, M., Dtsche. Apoth.-Ztg. 138 (38), 47-54 (1998).
- Boutekedjiret, C., Bentahar, F., Belabbes, R., Bessiere, J.M., Flavour Fragr. J. 18,481-484 (2003).
- Salido, S., Altarejos, J., Nogueras, M., Sanchez, A., Luque, P., J. Essent. Oil Res. 15, 10-14 (2003).
- Galle-Hoffmann, U., Konig, W.A., Dtsche. Apoth.-Ztg. 139 (3), 64-72 (1999).
- Kreck, M., Scharrer, A., Bilke, St., Mosandl, A., Flavour Frgr. J. 17, 32-40(2002).
- Mori, M., Ikeda, N., Kato, Y., Minamino, M., Watabe, K., YAKUGAKU ZASSHI 122 (3), 253-261 (2002).
- Shellie, R., Marriott, Ph., Zappia, G., Mondello, L., Dugo, G., J. Essent. Oil Res. 15, 305-312 (2003).
- Adam, K., Sivropoulou, A,, Kokkini, S., Lanaras, T., Arsenakis, M., J.Agric. Food Chem.46, 1739-1745 (1998).
- Baer, B., Analytik und Mikrobiologie des atherischen Ols verschiedener Kamillenarten, Thesis, Freie Universitat Berlin (1995).
- Baratta, T., Dorman, S., Deans, S., Figueiredo, A., Barroso, J., Ruberto, G., Flavour Fragr. J. 13, 235-244 (1998).
- Boesel, R., Pharmakologische, phytochemische und mikrobiologische Untersuchungen von Quecken wurzelstock Rhizoma Graminis (Erg. -B. 6) (Agropyron repens (L.) PALISOT DE BEAUVOIS, Poaceae), Thesis, Freie Universitaet Berlin (1991).
- Bourrel, C., Vilarm, G., Michel, G., Gaset, A., Rivista ltaliana 16/17, 1-15 (1995).
- Davidson, P., Parish, M., Food Technol. 1989, 148-155.
- Gabrielli, G., Loggini, F., Cioni, P., Giannaccini, B., Mancuso, E., Pharm. Res. Commun. 20, 37-40 (1988).
- Griffin, S., Grant, W., Markham, J., Leach, D., Flavour Fragr.J. 14, 323-332 (1999).
- Hammer, K., Carson, C., Riley, T., J.Appl.Microbiol. 86, 985-990 (1996).
- Hood, J .R., Wilkinson, J.M., Cavangh, M.A., J.Essent.Oil.Res. 15, 428-433 (2003).
- Illiev, S., Papanov, G., Malakov, P., Hristeva, P., Tomova, K., University of Plovdiv, Scientific works 21, No. 3, 105-112 (1983).
- Janssen, A.M., Scheffer, J.J.C., Baerheim Svendsen, A., Planta Med. 1987, 395-398.
- Jirovetz, L., Buchbauer, G., Stoyanova, A.S., Georgiev, E.V., Damianova, St.T., J. Agric. Food Chem. 51, 3854-3857 (2003).
- Johnson, T.R., Case, Ch.L., Laboratory Experiments in Microbiology - Brief Edition, 3rd Ed., 153-155, The Benjamin/Cummings Publishing Company, Inc., Redwood City (1992).
- Lis-Balchin, M., Deans, A., Eaglesham, E., Flavour Fragr.J. 13, 98-104 (1998).
- Neunaber, E., Phytochemische und mikrobiologische Untersuchungen von Propolis verschiedener Provenienz als Beitrag zur Kenntnis der Wirkprinzipien in Propolis, Thesis, Freie Universitat Berlin (1995).
- Paukova, T., Stoichev, I., Shabanova, R., Higher Institute of Flavor and Fragrance Industries, Plovdiv, Scientific works 20, No. 3, 305-314 (1973).
- Stendel, H., Seifen-Ole-Fette-Wachse 97, 736-738 (1971).
- Zaika, L., J.Food Safety 9, 97-118 (1988).
- Arctander, St., Perfume and Flavor Chemicals, Vol. I, II & III, Arctander Publication, Montclair (1969).
- Fazzalari, F.A., Compilation of Odor and Taste Threshold Values Data, American Society for Testing and Materials, Philadelphia (1978).
- Bauer, K., Garbe, D., Surburg, H., Common Fragrance and Flavor Materials, 3rd Ed., VCH, Weinheim (1997).
- Furia, T.E., Bellanca, N. (Eds.), Fenaroli's Handbook of Flavor Ingredients, 2nd Edition, Vol. I & II, CRC Press, Cleveland (1975).
- Sigma-Aldrich, Flavors & Fragrances, The Essence of Excellence, Sigma-Aldrich Co., Milwaukee (2003).
- Antimicrobial Testinqs, Gas Chromatoqraphic Analysis and Olfactorv Evaluation of an Essential Oil of Hop Cones (Humulus lupulus L.) from Bavaria and some of its main Compounds
Abstract Views :309 |
PDF Views:0
Authors
Leopold Jirovetz
1,
Stefanie Bail
1,
Gerhard Buchbauer
1,
Zapriana Denkova
2,
Alexander Slavchev
2,
Albena Stoyanova
3,
Erich Schmidt
4,
Margit Geissler
5
Affiliations
1 Department of Clinical Pharmacy and Diagnostics, University of Vienna, Althanstrasse 14, A-1090 Vienna, AT
2 University of Food Technology, Department of Microbiology, 26 Maritza Boulevard, 4002 Plovdiv, BG
3 University of Food Technology, Department of Essential Oils, 26 Maritza Boulevard, 4002 Plovdiv, BG
4 Kurt Kitzing GmbH, Hinterm Alten Schloss 21, D-86757 Wallerstein, DE
5 Department of GC and GC/MS, Albert-Hahn-Strasse 6-10, D-47269 Duisburg, DE
1 Department of Clinical Pharmacy and Diagnostics, University of Vienna, Althanstrasse 14, A-1090 Vienna, AT
2 University of Food Technology, Department of Microbiology, 26 Maritza Boulevard, 4002 Plovdiv, BG
3 University of Food Technology, Department of Essential Oils, 26 Maritza Boulevard, 4002 Plovdiv, BG
4 Kurt Kitzing GmbH, Hinterm Alten Schloss 21, D-86757 Wallerstein, DE
5 Department of GC and GC/MS, Albert-Hahn-Strasse 6-10, D-47269 Duisburg, DE
Source
Scientia Pharmaceutica, Vol 74, No 4 (2006), Pagination: 189-201Abstract
The essential oil of hop cones (Humulus lupulu L.) was analyzed by GC and GC-MS to assess the composition of volatiles and to evaluate olfactorially the principle aroma compounds. Myrcene (45.3%), α-humulene (31.2%) and β-caryophyllene (9.8%) were found to be the main constituents of this H. lupulus sample. The essential hop oil, the 3 main compounds and three minor concentrated constituents, isobutyl isobutyrate, geraniol and β-pinene, were tested for their antimicrobial activities against some different strains of Gram-positive and Gram-negative bacteria as well as the yeast Candida albicans by using agar diffusion and agar dilution method, respectively. The same was done using the phenolic aroma compound eugenol and the synthetic antibiotics ciproxinR, LidaprimR and tetracycline hydrochloride as reference-substance. It was found that the essential H. lupulus oil showed antimicrobial activities against the Gram-positive-bacteria Staphylococcus aureus and Enterococcus faecalis, the Gram-negative-bacteria Escherichia coli and Salmonella sp. as well as the yeast Candida albicans. This result was correlated to the antimicrobial testing of the mentioned main and minor constituents of the essential hop oil as well as of the 4 reference-compounds. The obtained data were discussed to get more insight into the influence of pure aroma compounds on the antimicrobial activities of essential oils.Keywords
Humulus lupulus L., Cones, Essential Oil, Composition, Antimicrobial Testing, Olfactory Evaluation, GC, GC-MS.References
- Jirovetz L, Buchbauer G, Stoyanova A, Denkova Z, Murgov I. Antimicrobial Testings and Chiral Phase Gas Chromatographic Analysis of Lavandula Oils and Related key compounds. Eurocosmet. 2004; 12(1): 30-33.
- Jirovetz L, Buchbauer G, Stoyanova A, Denkova Z, Murgov I. Antimicrobial testings and chiral phase gas chromatographic analysis of dill oils and related key compounds. Ernahrung/Nutrition 2004; 28(6): 257-260.
- Jirovetz L, Buchbauer G, Stoyanova A, Denkova Z, Murgov I, Schmidt E, et al. Antimicrobial testings and gas chromatographic analysis of pure oxygenated monoterpenes 1,8-cineole, α-terpineol, terpinen-4-ol and camphor as well as target compounds in essential oils of pine (Pinus pinaster), rosemary (Rosmarinus officinalis), tea tree (Melaleuca alternifolia). Sci Pharm. 2005; 73: 27-39.
- Jirovetz L, Buchbauer G, Stoyanova A, Denkova Z, Murgov I, Schmidt E, et al. In: Jirovetz L, Buchbauer G, editors. Processing, Analysis and Application of Essential Oils. Dehradun, 1ndia:Har Krishan Bhalla & Sons, 2005. p. 266-274.
- Jirovetz L, Buchbauer G, Denkova Z, Stoyanova A, Murgov 1, Lien HN, et al. Antimicrobial testings and gas chromatographic analysis of black pepper (Piper nigrum L.) and ginger (Zingiber officinale (L.) Rosc.) oleoresins from Vietnam. Eurocosmet. 2005; 13(1/2): 22-26.
- Jirovetz L, Buchbauer G, Denkova Z, Stoyanova Z, Georgiev EV, Langer R, Oregano-atherische Ole. Osterr. Apoth.-Ztg. 2005; 59(12): 584-589.
- Jirovetz L, Buchbauer G, Denkova Z, Stoyanova A, Murgov I, Schmidt E, et al. Comparative Investigations of Antimicrobial Activities and Compositions of Various Aroma Samples-A Short Review In: Govil JN, Singh VK, Arunachalam C, editors. Recent Progress in Medicinal Plants. Vol. 13. Search for Natural Drugs. Houston: Studium press; 2006. p. 449-472.
- Jirovetz L, Buchbauer G, Denkova Z, Slavchev A, Stoyanova A, Schmidt E. Chemical composition, antimicrobial activities and odor description of various Salvia sp. and Thuja sp. essential oils. Ernahrung/Nutrition 2006; 30(4): 152-159.
- Jirovetz L, Buchbauer G, Denkova Z, Stoyanova A, Murgov I, Gearon V, et al. Comparative study on the antimicrobial activities of different sandalwood essential oils of various origin. Flavour Frag J. 2006; 21: 465-468.
- Jirovetz L, Eller G, Buchbauer G, Schmidt E, Denkova Z, Stoyanova A, et al. Chemical composition, antimicrobial activities and odor description of some essential oils with characteristic floral-rosy scent and of their principal aroma compounds. In: Recent Res. Devel, Agronomy & Horticulture, Vol. 2, (1-12), Research Signpost, Trivandrum, India (2006).
- Bernotiene G., Nivinskiene O., Butkiene R, Mockute D. Chemical composition of essential oils of hops (Humulus lupulus L.) growing wild in Aukstaitija. Chemija 2004;15(2): 31-36.
- Eri S, Khoo B, Lech J, Hartman TG. Direct Thermal Desorption-Gas-Chromatogrphy and Gas Chromatography-Mass Spectrometry Profiling of Hop (Humulus lupulus L.). J Agric Food Chem. 2000; 48: 1140-1149.
- Field JA, Nickerson G, James DD, Heider C. Determination of Essential Oils in Hops by Headspace Solid-Phase Microextraction. J Agric Food Chem. 1996; 44: 1768-1772.
- Kac M, Kovacevic M, Presentation and determination of hop (Humulus lupus L.) cultivars by a min-max model on composition of hop essential oil. Monatsschr. Brauwiss. 2000; 53(9/10): 180-184.
- Kishimoto T, Wanikawa A, Kagami N, Kawatsura K. Analysis of Hop-Derived Terpenoids in Beer and Evaluation of Their Behavior Using the Stir Bar-Sorptive Extraction Method with GC-MS. J Agric Food Chem. 2005; 53: 4701-4707.
- Lermusieau G, Bulens M, Collin S. Use of GC-Olfactometry to Identify the Hop Aromatic Compounds in Beer. J Agric Food Chem. 2001; 49: 3867-3874.
- Lermusieau G, Collin S. Hop aroma extraction and analysis. Molecular Methods of Plant Analysis. 2002; 21: 69-88.
- Malizia RA, Molli JS, Cardell DA, Grau RJA. J. Essential Oil of Hop Cones (Humulus lupulus L.) Essent Oil Res. 1999; 11: 13-15.
- Schieberle P, Steinhaus M. Characterization of the odor-active constituents in fresh and processed hops (variety Spalter Select) ACS Sym Ser. 2001; 782: 23-32.
- Steinhaus M, Schieberle P. Comparison of the Most Odor-Active Compounds in Fresh and Dries Hop Cones (Humulus lupulus L,. Variety Spalter Select) Based on GC-Olfactometry and Odor Dilution Techniques. J Agric Food Chem. 2000; 48: 1776-1783.
- De Keukeleire D, Heyerick A. Prenylflavonoids account for intriguing biological activities of hops. Acta Hort. 2005; 668: 175-189.
- Stavri M, Schneider R, O'Donnell G, Lechner D, Bucar F, Gibbons, S. The Antimycobacterial Components of Hops (Humulus lupulus) and their Dereplication. Phytother Res. 2004; 18: 774-776.
- Tanaka Y, Kikuzaki H, Nakatani N. Antibacterial activity of essential oils and oleoresins of spices and herbs against pathogen bacteria in upper airway respiratory tract. Nippon Shokuhin Kagaku Gakkaishi 2002; 9(2): 67-76.
- Arctander S, editor. Perfume and Flavor Chemicals, Vol. I, II & III. Montclair Arctander Publication; 1969.
- Fazzalari FA, editor. Compilation of Odor and Taste Threshold Values Data. Philadelphia: American Society for Testing and Materials; 1978.
- Bauer K, Garbe Dl Surburg H, editors. Common Fragrance and Flavor Materials, 3rd Ed. Weinheim: VCH; 1997.
- Furia TE, Bellanca N, editors., Fenaroli's Handbook of Flavor Ingredients, 2nd Edition, Vol. I & II. Cleveland: CRC Press; 1975.
- Sigma-Aldrich, Flavors & Fragrances, The Essence of Excellence. Milwaukee: Sigma-Aldrich Co.; 2003.